Malignant Face Granuloma

What is a Malignant Granuloma of the Face?

Another name for pathology after the scientist who discovered it is Wegener’s granulomatosis. Many modern researchers deny its existence as a separate disease, and attribute it to the malignant form of periarteritis nodosa.

Symptoms of Malignant Face Granuloma

The first lesions develop in the mucous membranes of the nasal cavity, sometimes in the pharynx, in the larynx, on the surface of the tonsils, on the face. In the future, they apply to other places. The foci in appearance are nodes of various sizes, which disintegrate over time, the skin dies in these places, leaving ulcers with a constantly bleeding surface. A very characteristic sign of the disease is the development of inflammatory changes in the respiratory tract. If ulcers form on the palate, then in the future they can pierce it through.

Especially severe is kidney damage. In this case, sometimes quite extensive sections of renal tissue die. Of the vessels, arteries and veins of small sizes are most often affected. Growths on the type of warts appear on the inner surface of their walls, a large number of blood clots form. As a result, the lumen of the vessel is completely or partially blocked, the blood flow, the delivery of oxygen and nutrients to the tissues, in particular to the skin, are disrupted. The nodes on the skin and mucous membranes can have different sizes, located superficially deep. At the same time, hemorrhages of various sizes can be found – from pinpoint to rather large.

In most patients, the disease develops very quickly and soon leads to their death. Usually a significant depletion of the body occurs within a few months. The general well-being of the patient is disturbed, high fever develops.

Treatment of Malignant Face Granuloma

Adrenal cortex hormone preparations and antibacterial drugs are mainly used.


Always unfavorable. Cases of cure for the disease are very rare.